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国际皮肤性病学杂志(英文)【2020年第04期】

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International Journal of Dermatology and Vernereology(简称IJDV)于2018年创刊,是目前大陆地区第一本也是唯一的英文皮肤性病学期刊。IJDV旨在为皮肤性病学及相关领域的临床医生和研究人员提供一个国际性开放平台,促进本学科各个方向包括流行病、病因、诊断和治疗的全面交流。过去的几十年,国内皮肤性病学包括遗传学,流行病学等发展迅速,科研成果倍出,有国际学术交流的迫切需要,但令人遗憾的是,大陆地区没有一本自主产权的皮肤病学英文刊可以提供这样的平台。因此,中华医学会和中国医学科学院皮肤病医院(皮肤病研究所)联手将原来的中文刊《国际皮肤性病学杂志》改刊为全英文的IJDV。中华医学会是国内最大的医学组织,具有丰富的办刊经验和资源。皮肤病研究所是全国皮肤病和性病学专业机构,也是国家性病和麻风控制中心和WHO性传播疾病预防和控制合作中心。研究所具有国内皮肤病学最全面的亚学科,是国内皮肤性学学术和科研力量最强的研究机构之一。编辑部有丰富的办刊经验,出版《中华皮肤科杂志》在皮肤性病学影响因子排名第一。目前IJDV已经有了超过2万人的微信粉丝群并在持续增加,为其影响力的快速提升打下了良好的基础。IJDV正在和荷兰威科商谈合作出版,力争在3-5年内实现期刊的国际化。

A Case Report of Pemphigoid Nodularis as Masquerader of Neurotic Excoriations

2021-01-10 19:13:19 医药卫生 Tan C
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AbstractIntroduction:Pemphigoid nodularis is a rare clinical variant of bullous pemphigoid characterized by both prurigo nodularis-like lesions and pemphigoid-like blisters.Herein, we report a case of pemphigoid nodularis in a cognitively-impaired patient who has been managed as extensive prurigo nodularis with neurotic exocriations for many years.Case presentation:A 72-year-old Chinese man has been on follow-up at an outpatient Dermatology unit for extensive prurigo nodularis for past 4 to 5 years until an inpatient stay when he was admitted for labile mood and erratic behavior due to the intense pruritus and skin lesions. During the admission, the inpatient team noticed tense hemorrhagic blisters on his right thigh for which histological examination confirmed the diagnosis of bullous pemphigoid. He was treated with oral prednisolone, doxycycline, and nicotinamide, which led to clinical improvement.Discussion:Pemphigoid nodularis can be easily misdiagnosed as prurigo nodularis. We discuss clinical clues that can raise the suspicion of an underlying immunobullous disorder, including erythematous nodules with a much larger surface area affected by central erosions and ulceration. Pruritus associated with larger areas of erosions and ulceration is clues that lesions can be more than mere excoriations.Conclusion:It is important for clinicians to be aware of the presentation of prurigo nodularis in association with bullous pemphigoid such that effective treatment can be promptly instituted. This is especially illustrated in this case, as the treatment of bullous pemphigoid not only improved his skin condition but it also improved his psychological health and behavior with the resolution of itch.

AbstractIntroduction:Pemphigoid nodularis is a rare clinical variant of bullous pemphigoid characterized by both prurigo nodularis-like lesions and pemphigoid-like blisters.Herein, we report a case of pemphigoid nodularis in a cognitively-impaired patient who has been managed as extensive prurigo nodularis with neurotic exocriations for many years.Case presentation:A 72-year-old Chinese man has been on follow-up at an outpatient Dermatology unit for extensive prurigo nodularis for past 4 to 5 years until an inpatient stay when he was admitted for labile mood and erratic behavior due to the intense pruritus and skin lesions. During the admission, the inpatient team noticed tense hemorrhagic blisters on his right thigh for which histological examination confirmed the diagnosis of bullous pemphigoid. He was treated with oral prednisolone, doxycycline, and nicotinamide, which led to clinical improvement.Discussion:Pemphigoid nodularis can be easily misdiagnosed as prurigo nodularis. We discuss clinical clues that can raise the suspicion of an underlying immunobullous disorder, including erythematous nodules with a much larger surface area affected by central erosions and ulceration. Pruritus associated with larger areas of erosions and ulceration is clues that lesions can be more than mere excoriations.Conclusion:It is important for clinicians to be aware of the presentation of prurigo nodularis in association with bullous pemphigoid such that effective treatment can be promptly instituted. This is especially illustrated in this case, as the treatment of bullous pemphigoid not only improved his skin condition but it also improved his psychological health and behavior with the resolution of itch.